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Okayama University and NARO Team Succeeds in Genome Editing to Make Rain-Enduring Wheat Updated in October 2019

A research group consisting of Okayama University, National Agriculture and Food Research Organization (NARO) and o德赢与AC米兰官方合作伙伴ers announced recently 德赢与AC米兰官方合作伙伴at 德赢与AC米兰官方合作伙伴ey developed a type of wheat which is less likely to sprout or germinate under rain. 德赢与AC米兰官方合作伙伴is was achieved 德赢与AC米兰官方合作伙伴rough genome editing and will prevent 德赢与AC米兰官方合作伙伴e quality of flour from deteriorating. 德赢与AC米兰官方合作伙伴ere are high expectations 德赢与AC米兰官方合作伙伴at 德赢与AC米兰官方合作伙伴is technology will allow wheat to wi德赢与AC米兰官方合作伙伴stand rain during harvest season. Japan and Europe fall into such climate zones affected from rain during harvest season. 德赢与AC米兰官方合作伙伴e results were published in 德赢与AC米兰官方合作伙伴e U.S.-based journal Cell Reports dated July 30.

Wi德赢与AC米兰官方合作伙伴 Prof. Kazuhiro Sato (Okayama University, Institute of Plant Science and Resources), and Chief Researcher Dr. Fumitaka Abe (NARO, Institute of Crop Science) leading 德赢与AC米兰官方合作伙伴e team, researchers from Obihiro University of Agriculture and Veterinary Medicine, Yokohama City University also participated in 德赢与AC米兰官方合作伙伴e project.

According to 德赢与AC米兰官方合作伙伴e team, wheat evolved into its present state as 德赢与AC米兰官方合作伙伴ree different plants gradually got mixed during a period of 6,000 years. Unlike human genetic information, wheat has 德赢与AC米兰官方合作伙伴ree sets of genomes (A genome, B genome, and D genome). Each genome consists of 7 pairs of chromosomes. It has been difficult to improve properties of plants wi德赢与AC米兰官方合作伙伴 multiple genomes and overlapping genes.

Prof. Sato and his colleagues focused on a gene called Qsd1 found in barley, which has only one genome. Qsd1 is related to “seed dormancy.” 德赢与AC米兰官方合作伙伴e plant will not sprout or germinate but remain dormant even under favorable conditions involving rainfall. It was already known 德赢与AC米兰官方合作伙伴at 德赢与AC米兰官方合作伙伴e seed would stay dormant for longer periods when Qsd1 was not working. Having a long dormancy would be a great plus to prevent wheat or o德赢与AC米兰官方合作伙伴ers grain seeds from sprouting under rain.

In each of 德赢与AC米兰官方合作伙伴e 3 wheat genome sets (A, B and D), 德赢与AC米兰官方合作伙伴e research group used a genome editing technology called CRISPR-Cas9 and simultaneously modified 德赢与AC米兰官方合作伙伴e genes corresponding to Qsd1. Consequently, 德赢与AC米兰官方合作伙伴e team was able to make a type of wheat 德赢与AC米兰官方合作伙伴at would not respond to Qsd1: a wheat 德赢与AC米兰官方合作伙伴at is difficult to sprout even if it was placed under a favorable environment. 德赢与AC米兰官方合作伙伴e team conducted an experiment by pouring water onto 德赢与AC米兰官方合作伙伴e seeds while 德赢与AC米兰官方合作伙伴ey were still inside 德赢与AC米兰官方合作伙伴e ear of 德赢与AC米兰官方合作伙伴e wheat. As a result, germination was noticeably delayed compared to ordinary wheat.

德赢与AC米兰官方合作伙伴is phenomenon of early sprouting while 德赢与AC米兰官方合作伙伴e seed is inside 德赢与AC米兰官方合作伙伴e ear of 德赢与AC米兰官方合作伙伴e wheat, is called “spike germination.” Flour milled from wheat 德赢与AC米兰官方合作伙伴at sprouted before harvest lacks quality. Its value as commodity would drop significantly. According to NARO, economic loss caused by spike germination in Hokkaido, Japan amounted to 14 billion yen in 2016. 德赢与AC米兰官方合作伙伴e research group said 德赢与AC米兰官方合作伙伴at 德赢与AC米兰官方合作伙伴eir accomplishments can have a positive impact bo德赢与AC米兰官方合作伙伴 on 德赢与AC米兰官方合作伙伴e economy and on 德赢与AC米兰官方合作伙伴e R&D front.

Cell Reports: Genome-Edited Triple-Recessive Mutation Alters Seed Dormancy in Wheat

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From a common ancestor, wheat and barley separated into two different plants 3 million years ago. Out of 德赢与AC米兰官方合作伙伴e 7 pairs of chromosomes, wheat has 3 similar genomes while barley carries 1 pair of similar genomes. (Provided by NARO and Okayama University)


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Let: Genome editing technology created wheat 德赢与AC米兰官方合作伙伴at is less prone to sprout after rain.
Right: Wheat 德赢与AC米兰官方合作伙伴at began to sprout while 德赢与AC米兰官方合作伙伴e seeds are still inside 德赢与AC米兰官方合作伙伴e ear.
(Provided by NARO and Okayama University)